Mark,
It's great to hear that the advanced CIFS acceleration that we released in RiOS 3.0 helped improve your Revit performance. Let me explain what overlapping opens is and when it should and should not be used.
The new CIFS optimization released in RiOS 3.0 provides layer-7 acceleration for application environments that either break an oplock (opportunistic lock) or simply do not request an oplock in the first place. While it is rare that applications exhibit this behavior, some applications and certain operation contexts within the appplication will open a file multiple times within the application itself. When this happens, the oplock that maintains data consistency becomes broken for some timeframe and this defeats Riverbed's layer-7 acceleration. Data reduction and TCP-level optimizations continue to provide optimization. Specific applications known to exhibit this behavior include Solidworks and AutoDesk Revit, as demonstrated by your experience. Please note that not all operations within these applications exhibit this behavior so overlapping opens is not always needed.
The overlapping opens optimization that provides layer-7 acceleration in the face of these environments can be enabled/disabled by file type. It is not recommended for the general case.